
1.個人信息:
姓名:韓天燕,出生年月:1990.07,學(xué)歷:博士研究生,職稱:副教授。郵箱:1169808753@qq.com。通訊地址:石河子大學(xué)醫(yī)學(xué)院杏3樓B112辦公室
2.科研學(xué)術(shù)工作經(jīng)歷與教育背景:2023年12月畢業(yè)于空軍軍醫(yī)大學(xué),獲得醫(yī)學(xué)博士學(xué)位,期間從事于腫瘤靶向遞送系統(tǒng)在乳腺癌及其骨轉(zhuǎn)移瘤治療中的應(yīng)用研究。
3. 主要研究方向:
主要致力于靶向遞送系統(tǒng)的設(shè)計與開發(fā)、納米靶向遞送系統(tǒng)在惡性腫瘤治療中的應(yīng)用以及新疆地區(qū)高發(fā)性消化道腫瘤(食管癌)的發(fā)病機理和防治研究
4. 教學(xué)科研成果:
承擔(dān)本科生病理課程的教學(xué),年均課時量達120學(xué)時。
(1)教學(xué)科研項目
自治區(qū)“天池英才”青年博士項目(自治區(qū)級),主持。
石河子大學(xué)青年創(chuàng)新拔尖人才項目(校級),主持。
(2)論文
Tian-Yan Han, Meng-Lei Huan, Zedong Cai, Chen Li, Jingwen Wang, Si-Yuan Zhou, Wei He, Bang-Le Zhang. Nonviral genetic manipulation system with microenvironmental cascade sensitivity for the treatment of TNBC-associated metastatic bone tumor[J]. Chemical Engineering Journal, 2024, 499: 156162. (IF=13.40,中科院1區(qū))
Tian-Yan Han, Meng-Lei Huan, Ze-dong Cai, Wei He, Si-Yuan Zhou, Bang-Le Zhang. Polymer-initiating caveolae-mediated endocytosis and GSH-responsive MiR-34a gene delivery system for enhanced orthotopic triple negative breast cancer therapy[J]. Advanced Healthcare Materials, 2023, 12(32): 2302094. (IF=10.00,中科院2區(qū))
Tian-Yan Han, Li-Shuang Hou, Jia-Xin Li, Meng-Lei Huan, Si-Yuan Zhou, Bang-Le Zhang. Bone targeted miRNA delivery system for miR-34a with enhanced anti-tumor efficacy to bone-associated metastatic breast cancer[J]. International Journal of Pharmaceutics, 2023, 635: 122755. (IF=5.80,中科院2區(qū))
Han Tianyan, Yong Jinjiao, Liu Qiang, Gu Xiangshuai, Zhang Wannian, Yang Jianhong. Preparation and characterization of wet-milled cyclovirobuxine D nanosuspensions[J]. Journal of Thermal Analysis & Calorimetry, 2020, 139(3): 1959-1970.(IF=3.072,中科院3區(qū))
Fang Kou, Wei Wang, Xiaohong Zhu, Tian-Yan Han, Yajun Shi, Bang-Le Zhang.Construction of GSH-responsive polyethyleneimine-based delivery vector for effective gene transfection[J]. Nanotechnology, 2024, 35(41): 415102.
Zedong Cai, Meng-Lei Huan, Yao-Wen Zhang, Ting-Ting Zhao, Tian-Yan Han, Wei He, Si-Yuan Zhou, Bang-Le Zhang. Tumor targeted combination therapeutic system for the effective treatment of drug resistant triple negative breast cancer[J]. International Journal of Pharmaceutics, 2023, 636(Suppl C): 122821.
Yu-Hang Wan, Meng-Lei Huan, Chong-Xiao Yun, Tian-Yan Han, Si-Yuan Zhou, Xiao Song, Bang-Le Zhang. Construction of mPEI/pGPX4 gene therapeutic system for the effective treatment of acute lung injury[J]. Nanotechnology, 2023, 34(33): 335101.
Na Li, Tingting Fu, Wenling Fei, Tianyan Han, Xiangshuai Gu, Yanhui Hou Yanhua Liu, Jianhong Yang. Vitamin E D-alpha-tocopheryl polyethylene glycol 1000 succinate-conjugated liposomal docetaxel reverses multidrug resistance in breast cancer cells[J]. The Journal of Pharmacy and Pharmacology, 2019, 71(8): 1243-1254.
韓天燕,劉強,張萬年,楊建宏. 仙曲片粉體學(xué)性質(zhì)考察及處方設(shè)計[J]. 中成藥,2020,8: 1982-1986.
韓天燕,付亭亭,費文玲,郝俏君,張萬年,楊建宏. 基于質(zhì)量源于設(shè)計理念的仙曲片薄膜包衣工藝研究[J]. 中草藥,2018,11: 2564-2570.
付亭亭,韓天燕,左文寶,郝俏君,費文玲,彭曉東,楊建宏. 黑果枸杞顆粒成型工藝研究[J]. 中國新藥雜志,2018,13: 1560-1564.
(3)專利:
張邦樂,韓天燕,宦夢蕾,何煒,周四元,李嘉欣,李煜垚. 一種骨靶向基 因遞送系統(tǒng)的制備方法及其應(yīng)用: 中國,ZL202211252840.8[P]. 2025-01-03.
張邦樂,韓天燕,宦夢蕾,何煒,周四元,許經(jīng)良,翟曉沛. 一種協(xié)同治療骨轉(zhuǎn)移瘤的基因遞釋系統(tǒng)的制備方法及其應(yīng)用: 中國,CN202311737863.2[P]. 2025-01-03.
5.個人事跡:
自2024年10月入職石河子大學(xué)后,便決心扎根邊疆,致力于兵團醫(yī)學(xué)教育的發(fā)展,從事一線教學(xué)與科研工作。